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Journal article

Phenotypic consequences of a genetic predisposition to enhanced nitric oxide signaling

Abstract:
Background: Nitric oxide signaling plays a key role in the regulation of vascular tone and platelet activation. Here, we seek to understand the impact of a genetic predisposition to enhanced nitric oxide signaling on risk for cardiovascular diseases, thus informing the potential utility of pharmacological stimulation of the nitric oxide pathway as a therapeutic strategy. Methods: We analyzed the association of common and rare genetic variants in 2 genes that... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1161/circulationaha.117.028021

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Role:
Author
ORCID:
0000-0001-8402-7435
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Role:
Author
ORCID:
0000-0003-4026-8944
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Publisher:
American Heart Association Publisher's website
Journal:
Circulation Journal website
Volume:
137
Issue:
3
Pages:
222-232
Publication date:
2017-10-05
Acceptance date:
2017-09-25
DOI:
EISSN:
1524-4539
ISSN:
0009-7322
Pmid:
28982690
Source identifiers:
735046
Language:
English
Keywords:
Pubs id:
pubs:735046
UUID:
uuid:6238a8b0-9868-448b-a140-67bf9ec5e3bb
Local pid:
pubs:735046
Deposit date:
2019-01-18

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