Journal article
Phenotypic consequences of a genetic predisposition to enhanced nitric oxide signaling
- Abstract:
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Background: Nitric oxide signaling plays a key role in the regulation of vascular tone and platelet activation. Here, we seek to understand the impact of a genetic predisposition to enhanced nitric oxide signaling on risk for cardiovascular diseases, thus informing the potential utility of pharmacological stimulation of the nitric oxide pathway as a therapeutic strategy. Methods: We analyzed the association of common and rare genetic variants in 2 genes that... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
-
-
(Accepted manuscript, pdf, 868.5KB)
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(Accepted manuscript, pdf, 334.0KB)
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- Publisher copy:
- 10.1161/circulationaha.117.028021
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Authors
Funding
Bibliographic Details
- Publisher:
- American Heart Association Publisher's website
- Journal:
- Circulation Journal website
- Volume:
- 137
- Issue:
- 3
- Pages:
- 222-232
- Publication date:
- 2017-10-05
- Acceptance date:
- 2017-09-25
- DOI:
- EISSN:
-
1524-4539
- ISSN:
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0009-7322
- Pmid:
-
28982690
- Source identifiers:
-
735046
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:735046
- UUID:
-
uuid:6238a8b0-9868-448b-a140-67bf9ec5e3bb
- Local pid:
- pubs:735046
- Deposit date:
- 2019-01-18
Terms of use
- Copyright holder:
- American Heart Association, Inc
- Copyright date:
- 2017
- Notes:
- Copyright © 2017 American Heart Association, Inc. This is the accepted manuscript version of the article. The final version is available online from American Heart Association at: https://doi.org/10.1161/circulationaha.117.028021
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