Journal article
Fat-secreted ceramides regulate vascular redox state and influence outcomes in patients with cardiovascular disease
- Abstract:
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Background: Obesity is associated with increased cardiovascular risk; however, the potential role of dysregulations in the adipose tissue (AT) metabolome is unknown.
Objectives: We explored the role of dysregulation in the AT metabolome on vascular redox signalling and cardiovascular outcomes.
Methods: We screened for metabolites differentially secreted by thoracic (ThAT) and subcutaneous (ScAT) tissue of obese patients with ath... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, 2.9MB)
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(Supplementary materials, 3.1MB)
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- Publisher copy:
- 10.1016/j.jacc.2021.03.314
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Authors
Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Journal of the American College of Cardiology Journal website
- Volume:
- 77
- Issue:
- 20
- Pages:
- 2494–2513
- Publication date:
- 2021-05-17
- Acceptance date:
- 2021-03-26
- DOI:
- ISSN:
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0735-1097
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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1169867
- Local pid:
- pubs:1169867
- Deposit date:
- 2021-03-31
Terms of use
- Copyright holder:
- Akawi et al.
- Copyright date:
- 2021
- Rights statement:
- ©2021, The Authors. Published by Elsevier on Behalf of The American College of Cardiology Foundation. This is an Open Access Article under the CC BY-NC-ND License (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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