Thesis
Characterisation of macrophage infiltration into solid tumours via image analysis and computational modelling
- Abstract:
-
Macrophages are innate immune cells that play a key role in conditions as diverse as wound healing, atherosclerosis and cancer. In cancer, macrophages may be characterised as anti-tumour, promoting a wider immune response and phagocytosing tumour cells, or as pro-tumour, suppressing the immune response and promoting blood vessel growth and metastasis. The spatial distribution of macrophages inside a tumour correlates with patient prognosis and treatment response, and is hypothesised to b...
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Authors
Contributors
+ Byrne, H
Department:
Mathematical Institute
Role:
Supervisor
+ Waters, S
Department:
Mathematical Institute
Role:
Supervisor
+ Grau, V
Department:
IBME, University of Oxford
Role:
Supervisor
+ Mech, F
Department:
Roche Pharma Research and Early Development
Role:
Supervisor
+ Quaiser, T
Department:
Roche Pharma Research and Early Development
Role:
Supervisor
Funding
+ EPSRC/MRC Centre for Doctoral Training in Systems Approaches to Biomedical Science
More from this funder
Funding agency for:
Bull, J
Grant:
EP/G037280/1
+ Engineering & Physical Sciences Research Council
More from this funder
Funding agency for:
Bull, J
Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:6319ffed-8db3-4e10-924b-cfa677923d34
- Deposit date:
- 2019-07-01
Terms of use
- Copyright holder:
- Bull, J
- Copyright date:
- 2018
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