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Assessing the efficacy and safety of magnesium sulfate for management of autonomic nervous system dysregulation in Vietnamese children with severe hand foot and mouth disease

Abstract:

BACKGROUND:Brainstem encephalitis is a serious complication of hand foot and mouth disease (HFMD) in children. Autonomic nervous system (ANS) dysregulation and hypertension may occur, sometimes progressing to cardiopulmonary failure and death. Vietnamese national guidelines recommend use of milrinone if ANS dysregulation with Stage 2 hypertension develops. We wished to investigate whether magnesium sulfate (MgSO4) improved outcomes in children with HFMD if used earlier in the evolution of the...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s12879-019-4356-x

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Role:
Author
ORCID:
0000-0003-1553-7356
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Publisher:
BioMed Central Publisher's website
Journal:
BMC Infectious Diseases Journal website
Volume:
19
Article number:
737
Publication date:
2019-08-22
Acceptance date:
2019-08-05
DOI:
EISSN:
1471-2334
Pmid:
31438878
Source identifiers:
1048253
Language:
English
Keywords:
Pubs id:
pubs:1048253
UUID:
uuid:63498db2-3b25-441e-a3de-226353da67c9
Local pid:
pubs:1048253
Deposit date:
2019-08-31

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