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Heritability of haemodynamics in the ascending aorta

Abstract:

Blood flow in the vasculature can be characterised by dimensionless numbers commonly used to define the level of instabilities in the flow, for example the Reynolds number, Re. Haemodynamics play a key role in cardiovascular disease (CVD) progression. Genetic studies have identified mechanosensitive genes with causal roles in CVD. Given that CVD is highly heritable and abnormal blood flow may increase risk, we investigated the heritability of fluid metrics in the ascending aorta calculated us...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/s41598-020-71354-7

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Engineering and Physical Sciences Research Council More from this funder
Publisher:
Springer Nature Publisher's website
Journal:
Scientific Reports Journal website
Volume:
10
Issue:
1
Article number:
14356
Publication date:
2020-09-01
Acceptance date:
2020-06-25
DOI:
EISSN:
2045-2322
Pmid:
32873833
Language:
English
Keywords:
Pubs id:
1130759
Local pid:
pubs:1130759
Deposit date:
2020-11-09

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