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Journal article

Myofibroblasts are distinguished from activated skin fibroblasts by the expression of AOC3 and other associated markers

Abstract:

Pericryptal myofibroblasts in the colon and rectum play an important role in regulating the normal colorectal stem cell niche and facilitating tumor progression.Myofibroblasts previously have been distinguished from normal fibroblasts mostly by the expression of α; smooth muscle actin (α;SMA). We now have identified AOC3 (amine oxidase, copper containing 3), a surface monoamine oxidase, as a new marker of myofibroblasts by showing that it is the target protein of the myofibroblastreacting mAb...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1073/pnas.1603534113

Authors


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European Research Council More from this funder
Publisher:
National Academy of Sciences Publisher's website
Journal:
Proceedings of the National Academy of Sciences of the United States of America Journal website
Volume:
113
Issue:
15
Pages:
E2162-E2171
Publication date:
2016-04-12
Acceptance date:
2016-03-04
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
Source identifiers:
618261
Keywords:
Pubs id:
pubs:618261
UUID:
uuid:6546fa48-0054-4a71-aaf8-05580dd75fb6
Local pid:
pubs:618261
Deposit date:
2016-08-03

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