Journal article
Myofibroblasts are distinguished from activated skin fibroblasts by the expression of AOC3 and other associated markers
- Abstract:
-
Pericryptal myofibroblasts in the colon and rectum play an important role in regulating the normal colorectal stem cell niche and facilitating tumor progression.Myofibroblasts previously have been distinguished from normal fibroblasts mostly by the expression of α; smooth muscle actin (α;SMA). We now have identified AOC3 (amine oxidase, copper containing 3), a surface monoamine oxidase, as a new marker of myofibroblasts by showing that it is the target protein of the myofibroblastreacting mAb...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
European Research Council
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Bibliographic Details
- Publisher:
- National Academy of Sciences Publisher's website
- Journal:
- Proceedings of the National Academy of Sciences of the United States of America Journal website
- Volume:
- 113
- Issue:
- 15
- Pages:
- E2162-E2171
- Publication date:
- 2016-04-12
- Acceptance date:
- 2016-03-04
- DOI:
- EISSN:
-
1091-6490
- ISSN:
-
0027-8424
Item Description
- Keywords:
- Pubs id:
-
pubs:618261
- UUID:
-
uuid:6546fa48-0054-4a71-aaf8-05580dd75fb6
- Local pid:
- pubs:618261
- Source identifiers:
-
618261
- Deposit date:
- 2016-08-03
Terms of use
- Copyright holder:
- Hsia et al
- Copyright date:
- 2016
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