Journal article
The vacuolar pathway of long peptide cross-presentation can be TAP dependent
- Abstract:
-
The intracellular pathway of cross-presentation, which allows MHC class I–restricted presentation of peptides derived from exogenous Ags, remains poorly defined and may vary with the nature of the exogenous Ag and the type of APC. It can be cytosolic, characterized by proteasome and TAP dependency, or vacuolar, usually believed to be proteasome and TAP independent. Cross-presentation is particularly effective with long synthetic peptides, and we previously reported that the HLA-A2–restricted ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Publisher copy:
- 10.4049/jimmunol.1800353
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Authors
Bibliographic Details
- Publisher:
- American Association of Immunologists Publisher's website
- Journal:
- Journal of Immunology Journal website
- Volume:
- 202
- Issue:
- 2
- Pages:
- 451-459
- Publication date:
- 2019-01-15
- Acceptance date:
- 2018-11-12
- DOI:
- EISSN:
-
1550-6606
- ISSN:
-
0022-1767
- Source identifiers:
-
953385
Item Description
- Language:
- English
- Pubs id:
-
pubs:953385
- UUID:
-
uuid:658b3100-1505-43b3-ad32-c12f6c548ef7
- Local pid:
- pubs:953385
- Deposit date:
- 2018-12-19
Terms of use
- Copyright holder:
- American Association of Immunologists
- Copyright date:
- 2019
- Notes:
- Copyright © 2019 by The American Association of Immunologists, Inc.
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