Thesis
Statistical methods for mapping complex traits
- Abstract:
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The first section of this thesis addresses the problem of simultaneously identifying multiple loci that are associated with a trait, using a Bayesian Markov Chain Monte Carlo method. It is applicable to both case/control and quantitative data. I present simulations comparing the methods to standard frequentist methods in human case/control and mouse QTL datasets, and show that in the case/control simulations the standard frequentist method out performs my model for all but the highest ef...
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Funding
Bibliographic Details
- Publication date:
- 2014
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- Oxford University, UK
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:65f392ba-1b64-4b00-8871-7cee98809ce1
- Local pid:
- ora:8982
- Deposit date:
- 2014-09-26
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Terms of use
- Copyright holder:
- Allchin, L
- Copyright date:
- 2014
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