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Using fluid walls for single-cell cloning provides assurance in monoclonaliy

Abstract:

Single-cell isolation and cloning are essential steps in many applications, ranging from the production of biotherapeutics to stem cell therapy. Having confidence in monoclonality in such applications is essential from both research and commercial perspectives, for example, to ensure that data are of high quality and regulatory requirements are met. Consequently, several approaches have been developed to improve confidence in monoclonality. However, ensuring monoclonality using standard well ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1177/2472630319891135

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Role:
Author
Publisher:
SAGE Publications Publisher's website
Journal:
SLAS technology Journal website
Volume:
25
Issue:
3
Pages:
267-275
Publication date:
2019-12-09
Acceptance date:
2019-12-04
DOI:
EISSN:
2472-6311
ISSN:
2472-6303
Pmid:
31815577
Language:
English
Keywords:
Pubs id:
1077870
Local pid:
pubs:1077870
Deposit date:
2020-01-29

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