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Spatiotemporally super-resolved volumetric traction force microscopy

Abstract:

Quantification of mechanical forces is a major challenge across biomedical sciences. Yet such measurements are essential to understanding the role of biomechanics in cell regulation and function. Traction force microscopy remains the most broadly applied force probing technology but typically restricts itself to single-plane two-dimensional quantifications with limited spatiotemporal resolution. Here, we introduce an enhanced force measurement technique combining 3D super-resolution fluoresce...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1021/acs.nanolett.9b01196

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Sub department:
Weatherall Institute of Molecular Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Sub department:
Weatherall Institute of Molecular Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Role:
Author
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Publisher:
American Chemical Society Publisher's website
Journal:
Nano Letters Journal website
Volume:
19
Issue:
7
Pages:
4427-4434
Publication date:
2019-06-14
Acceptance date:
2019-06-12
DOI:
EISSN:
1530-6992
ISSN:
1530-6984
Pmid:
31199151
Source identifiers:
1015646
Language:
English
Keywords:
Pubs id:
pubs:1015646
UUID:
uuid:67027259-66ac-4fbc-9afc-cad6f15e0ce0
Local pid:
pubs:1015646
Deposit date:
2019-08-07

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