Journal article
mwr Xer site-specific recombination is hypersensitive to DNA supercoiling
- Abstract:
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The multiresistance plasmid pJHCMW1, first identified in a Klebsiella pneumoniae strain isolated from a neonate with meningitis, includes a Xer recombination site, mwr, with unique characteristics. Efficiency of resolution of mwr-containing plasmid dimers is strongly dependent on the osmotic pressure of the growth medium. An increase in supercoiling density of plasmid DNA was observed as the osmotic pressure of the growth culture decreased. Reporter plasmids containing directly repeated mwr, ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Publisher copy:
- 10.1093/nar/gkp208
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Authors
Funding
+ LA Basin Minority Health and Health Disparities International Research Training Program
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Funding agency for:
Tran, T
+ LA Basin Minority Health and Health Disparities International Research Training Program
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Funding agency for:
Sorto, N
+ LA Basin Minority Health and Health Disparities International Research Training Program
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Funding agency for:
Newmark, J
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Bibliographic Details
- Publisher:
- Oxford University Press Publisher's website
- Journal:
- Nucleic Acids Research Journal website
- Volume:
- 37
- Issue:
- 11
- Pages:
- 3580-3587
- Publication date:
- 2009-06-01
- DOI:
- EISSN:
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1362-4962
- ISSN:
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0305-1048
Item Description
- Language:
- English
- Subjects:
- UUID:
-
uuid:68eb7c61-1440-4826-ad02-d832c8372717
- Local pid:
- ora:3024
- Deposit date:
- 2009-11-05
Related Items
Terms of use
- Copyright holder:
- S Trigueros et al
- Copyright date:
- 2009
- Notes:
- Citation: Trigueros, S. et al. (2009). 'mwr Xer site-specific recombination is hypersensitive to DNA supercoiling', Nucleic Acids Research, 37(11), 3580-3587. [Available at http://nar.oxfordjournals.org/]. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
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