Journal article
Protein protein interactions, evolutionary rate, abundance and age
- Abstract:
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Background: Does a relationship exist between a protein's evolutionary rate and its number of interactions? This relationship has been put forward many times, based on a biological premise that a highly interacting protein will be more restricted in its sequence changes. However, to date several studies have voiced conflicting views on the presence or absence of such a relationship. Results: Here we perform a large scale study over multiple data sets in order to demonstrate that the major rea...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 978.2KB)
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- Publisher copy:
- 10.1186/1471-2105-7-128
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Authors
Funding
+ Engineering and Physical Sciences Research Council
More from this funder
Funding agency for:
Saeed, R
Bibliographic Details
- Publisher:
- BioMed Central Publisher's website
- Journal:
- BMC Bioinformatics Journal website
- Volume:
- 7
- Article number:
- 128
- Publication date:
- 2006-03-01
- DOI:
- ISSN:
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1471-2105
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:69275bff-17ee-4ac4-a0bf-aa8166a7dd42
- Local pid:
- ora:1808
- Deposit date:
- 2008-03-20
Related Items
Terms of use
- Copyright holder:
- Ramazan Saeed & Charlotte M Deane
- Copyright date:
- 2006
- Notes:
- © 2006 Saeed and Deane; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Citation: Saeed, R. & Deane, C. M. (2006). 'Protein protein interactions, evolutionary rate, abundance and age', BMC Bioinformatics, 7: 128. [Available at http://www.biomedcentral.com/1471-2105/7/128].
- Licence:
- CC Attribution (CC BY)
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