Thesis
Structure of the RNA-dependent RNA polymerase from influenza C virus
- Abstract:
-
The influenza virus causes a disease that kills approximately 500,000 people worldwide each year. Influenza is a negative-sense RNA virus that encodes its own RNA-dependent RNA polymerase. This protein (FluPol) carries out both genome replication and viral transcription. Therefore, like the L-proteins of non-segmented negative-sense RNA (nsRNA) viruses, FluPol also contains mRNA capping and polyadenylation functionality. In FluPol, capping is achieved by snatching cap structures from cellu...
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Authors
Contributors
+ Fodor, E
Division:
MSD
Department:
Pathology Dunn School
Role:
Supervisor
+ Grimes, J
Division:
MSD
Department:
Pathology Dunn School
Role:
Supervisor
Funding
Bibliographic Details
- Publication date:
- 2014
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- Oxford University, UK
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:694e16a6-f94e-4375-a1f9-7e250aea7343
- Local pid:
- ora:11302
- Deposit date:
- 2015-04-29
Terms of use
- Copyright holder:
- Hengrung, N
- Copyright date:
- 2014
- Notes:
- This thesis is not currently available in ORA.
- Licence:
- CC Attribution (CC BY)
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