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Journal article

Harmonized genome wide typing of tubercle bacilli using a web-based gene-by-gene nomenclature system

Abstract:

Background

Global tuberculosis (TB) control is challenged by uncontrolled transmission of Mycobacteriumtuberculosis complex (Mtbc) strains, esp. of multidrug (MDR) or extensively resistant (XDR) variants. Precise analysis of transmission networks is the basis to trace outbreak M/XDR clones and improve TB control. However, classical genotyping tools lack discriminatory power due to the high similarity of strains of particular successful lineages, e.g. Beijing or outbreak strains. ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1016/j.ebiom.2018.07.030

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Subgroup:
NDM Experimental Medicine
Role:
Author
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German Center for Infection Research More from this funder
Publisher:
Elsevier Publisher's website
Journal:
EBioMedicine Journal website
Volume:
34
Pages:
131-138
Publication date:
2018-08-13
Acceptance date:
2018-07-20
DOI:
EISSN:
2352-3964
ISSN:
2352-3964
Pubs id:
pubs:909969
URN:
uri:697cd6a7-0523-4c83-be26-2250491aa9bf
UUID:
uuid:697cd6a7-0523-4c83-be26-2250491aa9bf
Local pid:
pubs:909969

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