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Control of cyclin C levels during development of Dictyostelium

Abstract:

Background: Cdk8 and its partner cyclin C form part of the mediator complex which links the basal transcription machinery to regulatory proteins. The pair are required for correct regulation of a subset of genes and have been implicated in control of development in a number of organisms including the social amoeba Dictyostelium discoideum. When feeding, Dictyostelium amoebae are unicellular but upon starvation they aggregate to form a multicellular structure which develop...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pone.0010543

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Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
Wellcome Trust More from this funder
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS ONE Journal website
Volume:
5
Issue:
5
Article number:
e10543
Publication date:
2010-05-01
DOI:
EISSN:
1932-6203
Language:
English
Keywords:
Subjects:
UUID:
uuid:69e581ea-e994-4458-a39c-e3d5653f30ae
Local pid:
ora:5175
Deposit date:
2011-03-25

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