Journal article icon

Journal article

Presentation by myoblasts of an epitope from endogenous acetylcholine receptor indicates a potential role in the spreading of the immune response.

Abstract:

It is generally considered that myoblasts are unable to prime naive T cell responses without help from professional antigen-presenting cells (APC). However, their ability to present endogenous antigens to previously primed T lymphocytes in the secondary phase of a T cell response has not been well studied. We show here that primary human myoblasts, when stimulated with IFNgamma to express class II MHC, can present an endogenous epitope, probably an acetylcholine receptor (AChR) peptide, to a ...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Journal:
Journal of neuroimmunology
Volume:
115
Issue:
1-2
Pages:
127-134
Publication date:
2001-04-01
DOI:
EISSN:
1872-8421
ISSN:
0165-5728
Source identifiers:
241122
Language:
English
Keywords:
Pubs id:
pubs:241122
UUID:
uuid:6a97caba-cba7-422d-84af-cb859b063b45
Local pid:
pubs:241122
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP