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Thesis

Advanced spectroscopic imaging techniques for X-nuclei cardiac magnetic resonance imaging

Abstract:

Changes to cardiac metabolism are an important component of heart failure. Understanding these metabolic changes is therefore critical to developing treatments for the failing heart, particularly pharmaceuticals, or other interventions, which aim to restore normal metabolism. A combination of hyperpolarized 13C and 31P magnetic resonance spectroscopic imaging (MRSI) enables quantification of both the substrate usage (13C) and energy output (31P) of cardiac metabolism, allowing a full pictu...

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Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author

Contributors

Role:
Supervisor
ORCID:
0000-0002-0780-8905
Role:
Supervisor
ORCID:
0000-0003-2567-3642
Role:
Supervisor
ORCID:
0000-0002-6258-1299
Role:
Supervisor
Role:
Examiner
ORCID:
0000-0001-6272-8783
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
Deposit date:
2022-02-04

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