Journal article
Different modes of variation for each BG lineage suggest different functions.
- Abstract:
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Mammalian butyrophilins have various important functions, one for lipid binding but others as ligands for co-inhibition of αβ T cells or for stimulation of γẟ T cells in the immune system. The chicken BG homologues are dimers, with extracellular immunoglobulin variable (V) domains joined by cysteines in the loop equivalent to complementarity-determining region 1 (CDR1). BG genes are found in three genomic locations: BG0 on chromosome 2, BG1 in the classical MHC (the BF-BL region) and many BG ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 1.6MB)
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- Publisher copy:
- 10.1098/rsob.160188
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Authors
Funding
Biotechnology and Biological Sciences Research Council
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Bibliographic Details
- Publisher:
- Royal Society Publisher's website
- Journal:
- Open Biology Journal website
- Volume:
- 6
- Issue:
- 9
- Publication date:
- 2016-09-01
- Acceptance date:
- 2016-08-17
- DOI:
- ISSN:
-
2046-2441
- Pmid:
-
27628321
- Source identifiers:
-
646028
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:646028
- UUID:
-
uuid:6d465e9b-fda0-4b4d-b5b9-16cf0ea408fc
- Local pid:
- pubs:646028
- Deposit date:
- 2016-10-24
Terms of use
- Copyright holder:
- Lea et al
- Copyright date:
- 2016
- Notes:
- © 2016 The Authors. Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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