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Genome-wide analysis identifies 12 loci influencing human reproductive behavior

Abstract:

The genetic architecture of human reproductive behavior—age at first birth (AFB) and number of children ever born (NEB)—has a strong relationship with fitness, human development, infertility and risk of neuropsychiatric disorders. However, very few genetic loci have been identified, and the underlying mechanisms of AFB and NEB are poorly understood. We report a large genome-wide association study of both sexes including 251,151 individuals for AFB and 343,072 individuals for NEB. We identifie...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/ng.3698

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Institution:
University of Oxford
Division:
SSD
Department:
Sociology
Role:
Author
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Institution:
University of Oxford
Division:
SSD
Department:
Sociology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
SSD
Department:
Sociology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
HUMS
Department:
Medieval & Modern Languages Faculty
Sub department:
German
Role:
Author
More by this author
Institution:
University of Oxford
Division:
HUMS
Department:
Medieval & Modern Languages Faculty
Sub department:
German
Role:
Author
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Publisher:
Nature Publishing Group Publisher's website
Journal:
Nature Genetics Journal website
Volume:
48
Issue:
12
Pages:
1462-1472
Publication date:
2016-10-31
Acceptance date:
2016-09-22
DOI:
EISSN:
1546-1718
ISSN:
1061-4036
Source identifiers:
655078
Keywords:
Pubs id:
pubs:655078
UUID:
uuid:6d96929d-f886-4e73-a37b-4321371cf3ad
Local pid:
pubs:655078
Deposit date:
2016-10-25

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