Journal article
L-Carnitine stimulates in vivo carbohydrate metabolism in the Type 1 diabetic heart as demonstrated by hyperpolarized MRI
- Abstract:
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The diabetic heart is energetically and metabolically abnormal, with increased fatty acid oxidation and decreased glucose oxidation. One factor contributing to the metabolic dysfunction in diabetes may be abnormal handling of acetyl and acyl groups by the mitochondria. L-carnitine is responsible for their transfer across the mitochondrial membrane, therefore, supplementation with L-carnitine may provide a route to improve the metabolic state of the diabetic heart. The primary aim of this stud...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, 2.9MB)
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- Publisher copy:
- 10.3390/metabo11030191
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Authors
Bibliographic Details
- Publisher:
- MDPI Publisher's website
- Journal:
- Metabolites Journal website
- Volume:
- 11
- Issue:
- 3
- Article number:
- 191
- Publication date:
- 2021-03-23
- Acceptance date:
- 2021-03-19
- DOI:
- EISSN:
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2218-1989
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
1169774
- Local pid:
- pubs:1169774
- Deposit date:
- 2021-04-06
Terms of use
- Copyright holder:
- Savic et al.
- Copyright date:
- 2021
- Rights statement:
- ©2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).
- Licence:
- CC Attribution (CC BY)
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