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Journal article

Funders improved the management of learning and clustering effects through design and analysis of randomized trials involving surgery

Abstract:
Objective The objective of this study was to provide insight into current practice in planning for, and acknowledging, the presence of learning and clustering effects, by treating center and surgeon, when developing randomized surgical trials.

Study Design and Setting Complexities associated with delivering surgical interventions, such as clustering effects, by center or surgeon, and surgical learning should be considered at trial design. Main tria... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.jclinepi.2019.05.007

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Centre for Statistics in Medicine
Oxford college:
St Hugh's College
Role:
Author
ORCID:
0000-0002-4156-6989
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National Institute for Health Research More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Journal of Clinical Epidemiology Journal website
Volume:
113
Pages:
28-35
Publication date:
2019-05-20
Acceptance date:
2019-05-15
DOI:
ISSN:
1878-5921
Source identifiers:
998723
Keywords:
Pubs id:
pubs:998723
UUID:
uuid:7096e6a0-8c60-4ccd-b693-8f45920ff468
Local pid:
pubs:998723
Deposit date:
2019-05-15

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