Journal article
High level antibody response to pandemic influenza H1N1/09 virus is associated with interferon-induced transmembrane protein-3 rs12252-CC in young adults
- Abstract:
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Background
The C allele of the interferon-induced transmembrane protein-3 (IFITM3) SNP rs12252, a common allele in South East Asia and China, is strongly associated with severe influenza infection. However, despite the high occurrence of rs12252-CC genotype in Chinese population (~25%), severe influenza infection is rare. The aim of study is to determine whether rs12252-CC individuals have pre-existing antibody responses to previous seasonal influenza infections.
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 1.0MB)
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- Publisher copy:
- 10.3389/fcimb.2018.00134
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Authors
Funding
National Natural Science Foundation of China
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Beijing Municipal Science and Technology Commission
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Beijing Municipal Administration of Hospitals
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Bibliographic Details
- Publisher:
- Frontiers Media Publisher's website
- Journal:
- Frontiers in Cellular and Infection Microbiology Journal website
- Volume:
- 8
- Issue:
- MAY
- Pages:
- 134
- Publication date:
- 2018-05-15
- Acceptance date:
- 2018-04-18
- DOI:
- EISSN:
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2235-2988
- ISSN:
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2235-2988
- Pmid:
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29868492
- Source identifiers:
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854591
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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pubs:854591
- UUID:
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uuid:70a3d085-12b3-4017-a8b2-bb557f77cee8
- Local pid:
- pubs:854591
- Deposit date:
- 2018-06-21
Terms of use
- Copyright holder:
- Dong et al
- Copyright date:
- 2018
- Notes:
- Copyright © 2018 Qin, Wang, Li, Zhao, Peng, Wellington, Dai, Sun, Sun, Liu, McMichael, Dong and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
- Licence:
- CC Attribution (CC BY)
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