Journal article
Changes in brain Glx in depressed bipolar patients treated with lamotrigine: a proton MRS study
- Abstract:
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Background Lamotrigine is a useful treatment in bipolar depression but requires several weeks of dose titration before its clinical effects can be assessed. Animal experimental studies suggest that lamotrigine lowers glutamate release. The aim of the current study was to assess the effect of lamotrigine on brain glutamate in depressed bipolar patients and to determine whether baseline glutamate could be used to predict clinical response.
Methods We... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 440.7KB)
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- Publisher copy:
- 10.1016/j.jad.2018.12.092
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Authors
Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Journal of Affective Disorders Journal website
- Volume:
- 246
- Pages:
- 418-421
- Publication date:
- 2018-12-25
- Acceptance date:
- 2018-12-24
- DOI:
- EISSN:
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1573-2517
- ISSN:
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0165-0327
- Source identifiers:
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955223
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:955223
- UUID:
-
uuid:72b8da95-4899-4f2a-a4d7-61d0fe03d8d4
- Local pid:
- pubs:955223
- Deposit date:
- 2018-12-29
Terms of use
- Copyright holder:
- Godlewska et al
- Copyright date:
- 2018
- Notes:
- © 2019 The Authors. Published by Elsevier B.V. Under a Creative Commons license
- Licence:
- CC Attribution (CC BY)
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