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Isolation, separation, identification, and quantification of bioactive methylated flavone regioisomers by UHPLC-MS/MS

Abstract:

Methylated flavones, commonly found in many plants of the Brassicaceae family, have potent antioxidant and anticancer activity with diverse therapeutic potential. However, the specific regioisomers of methylated flavones can have significantly different biochemical and potentially therapeutic properties as shown by various bioassays but analytically differentiating these compounds has been technically challenging and rarely reported. In this study, we demonstrate differentiation and identific...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/ansa.202100016

Authors


More by this author
Institution:
University of Oxford
Department:
Plant Sciences
Sub department:
Biochemistry
Oxford college:
Magdalen College
Role:
Author
ORCID:
0000-0002-6628-323X
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Oxford college:
Merton College
Role:
Author
ORCID:
0000-0003-4733-1205
John Fell Fund More from this funder
John Fell Fund More from this funder
Publisher:
Wiley Publisher's website
Journal:
Analytical Science Advances Journal website
Volume:
2
Issue:
7-8
Pages:
364-372
Publication date:
2021-05-05
Acceptance date:
2021-04-15
DOI:
EISSN:
2628-5452
Language:
English
Keywords:
Pubs id:
1176800
Local pid:
pubs:1176800
Deposit date:
2021-07-06

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