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Mesenchymal stromal cells are retained in the porcine renal cortex independently of their metabolic state after renal intra-arterial infusion

Abstract:

The regenerative capacities of mesenchymal stromal cells (MSCs) make them suitable for renal regenerative therapy. The most common delivery route of MSC is through intravenous infusion, which is associated with off-target distribution. Renal intra-arterial delivery offers a targeted therapy, but limited knowledge is available regarding the fate of MSCs delivered through this route. Therefore, we studied the efficiency and tissue distribution of MSCs after renal intra-arterial delivery to a po...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1089/scd.2019.0105

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Role:
Author
ORCID:
0000-0003-1062-3343
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Role:
Author
ORCID:
0000-0002-3774-4471
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Lundbeck Foundation More from this funder
Publisher:
Mary Ann Liebert Publisher's website
Journal:
Stem Cells and Development Journal website
Volume:
28
Issue:
18
Pages:
1224-1235
Publication date:
2019-09-16
Acceptance date:
2020-07-07
DOI:
EISSN:
1557-8534
ISSN:
1547-3287
Pmid:
31280676
Language:
English
Keywords:
Pubs id:
1041546
Local pid:
pubs:1041546
Deposit date:
2020-10-21

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