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On the role of receptor downregulation and costimulation in shaping the T cell response

Abstract:

T cells are critical decision-makers in the immune system and their activation determines whether a cell or molecule constitutes a threat to the body and needs to be eliminated or whether it should be ignored and tolerated by the immune system. Many molecules that play a role in T cell activation and their interactions with each other have been identified, but an overall understanding of the decision-making processes that lead to changes in T cell behaviour remain enigmatic. We are st...

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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Keywords:
Subjects:
UUID:
uuid:76ce2cf5-cb2c-45b7-9f2e-d0c2d78134ee
Deposit date:
2019-02-07

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