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Thesis

Coarse-grained modelling of a DNA origami force sensor

Abstract:

We have simulated large-scale DNA nanostructures using the oxDNA software which uses coarse-graining at the nucleotide level. These simulations can complement experiments as they typically allow greater structural resolution and give access to a range of properties that are otherwise hard to measure (e.g. internal forces).

To address the challenges associated with parallelised force spectroscopy, we report the development of a bottom-up approach for manipulating the mechanical forc...

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Division:
MPLS
Department:
Chemistry
Sub department:
Physical & Theoretical Chem
Role:
Author

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Physical & Theoretical Chem
Oxford college:
Queen's College
Role:
Supervisor
ORCID:
0000-0002-2226-9524
Type of award:
MSc by Research
Level of award:
Masters
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
Deposit date:
2022-04-25

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