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Evidence for a vascular contribution to diffusion FMRI at high b value.

Abstract:

Recent work has suggested that diffusion-weighted functional magnetic resonance imaging (FMRI) with strong diffusion weighting (high b value) detects neuronal swelling that is directly related to neuronal firing. This would constitute a much more direct measure of brain activity than current methods and represent a major advance in neuroimaging. However, it has not been firmly established that the observed signal changes do not reflect residual vascular effects, which are known to exist at lo...

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Publication status:
Published

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Publisher copy:
10.1073/pnas.0707257105

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
Journal:
Proceedings of the National Academy of Sciences of the United States of America
Volume:
104
Issue:
52
Pages:
20967-20972
Publication date:
2007-12-01
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
Source identifiers:
21209
Language:
English
Keywords:
Pubs id:
pubs:21209
UUID:
uuid:7749d567-983a-48b8-a861-f58a3ceb6039
Local pid:
pubs:21209
Deposit date:
2012-12-19

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