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Insulin signalling mediates the response to male-induced harm in female Drosophila melanogaster.

Abstract:

Genetic manipulations in nutrient-sensing pathways are known to both extend lifespan and modify responses to environmental stressors (e.g., starvation, oxidative and thermal stresses), suggesting that similar mechanisms regulate lifespan and stress resistance. However, despite being a key factor reducing female lifespan and affecting female fitness, male-induced harm has rarely been considered as a stressor mediated by nutrient sensing pathways. We explored whether a lifespan-extending manipu...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/srep30205

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More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Role:
Author
Publisher:
Nature Publishing Group Publisher's website
Journal:
Scientific Reports Journal website
Volume:
6
Pages:
30205
Publication date:
2016-07-01
Acceptance date:
2016-06-29
DOI:
ISSN:
2045-2322
Language:
English
Keywords:
Pubs id:
pubs:636580
UUID:
uuid:778fc98e-67f2-42a6-9caa-860768e0e4f9
Local pid:
pubs:636580
Source identifiers:
636580
Deposit date:
2016-08-05

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