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Kinetics of Plasma Viremia and Soluble Nonstructural Protein 1 Concentrations in Dengue: Differential Effects According to Serotype and Immune Status

Abstract:

We describe the magnitude and kinetics of plasma viremia and nonstructural protein 1 (sNS1) levels in sequential samples from 167 children with acute dengue, enrolled early in a community study in Vietnam. All children recovered fully, and only 5 required hospitalization. Among those with dengue virus type 1 (DENV-1), plasma viremia was significantly greater in primary (49) than secondary (44) infections and took longer to resolve. In primary DENV-2 and 3 infections, viremia was significantly...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/infdis/jir014

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084368/Wellcome Trust More from this funder
/Wellcome Trust More from this funder
Publisher:
Oxford University Press Publisher's website
Journal:
Journal of Infectious Diseases Journal website
Volume:
203
Issue:
9
Pages:
1292-1300
Publication date:
2011-02-18
Acceptance date:
2010-11-30
DOI:
EISSN:
1537-6613
ISSN:
0022-1899
Pmid:
21335562
Source identifiers:
120136
Language:
English
Keywords:
Pubs id:
pubs:120136
UUID:
uuid:784ea2a1-9a25-415d-bf0f-cf315ae7e19c
Local pid:
pubs:120136
Deposit date:
2017-06-07

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