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Antiplatelet treatment after transient ischemic attack and ischemic stroke in patients with cerebral microbleeds in 2 large cohorts and an updated systematic review

Abstract:

Background and Purpose

Purpose—In patients with transient ischemic attack/ischemic stroke, microbleed burden predicts intracerebral hemorrhage (ICH), and ischemic stroke, but implications for antiplatelet treatment are uncertain. Previous cohort studies have had insufficient follow-up to assess the time course of risks, have not stratified risks by antithrombotic use, and have not reported extracranial bleeds or functional outcome of ICH versus ischemic stroke.

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1161/strokeaha.117.020104

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
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British Heart Foundation More from this funder
Wolfson Foundation More from this funder
National Institute for Health Research More from this funder
Wellcome Trust More from this funder
Horizon 2020 More from this funder
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Publisher:
American Heart Association Publisher's website
Journal:
Stroke Journal website
Volume:
49
Issue:
6
Pages:
1434-1442
Publication date:
2018-05-10
Acceptance date:
2018-04-10
DOI:
EISSN:
1524-4628
ISSN:
0039-2499
Pmid:
29748422
Language:
English
Keywords:
Pubs id:
pubs:853111
UUID:
uuid:7a76bcc5-87cd-46c9-ae16-7038293bbc0d
Local pid:
pubs:853111
Deposit date:
2018-06-28

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