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Thesis

Modulation of regulatory T cell function through specific molecular pathways in transplantation

Abstract:

Regulatory T cells (Tregs) are crucial mediators of immune homeostasis that have shown immense promise as a cellular therapy for immune-mediated pathologies such as transplant rejection. Methods to optimise current Treg-based therapies are critical for its successful and widespread translation to the clinical setting. The aim of this study was to investigate the role of two molecular pathways for the modulation of Treg biology and function.

In the first part of this study, the role...

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Division:
MSD
Department:
Surgical Sciences
Role:
Author

Contributors

Role:
Supervisor
ORCID:
0000-0002-8279-7732
Role:
Supervisor
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Funding agency for:
Issa, F
Grant:
11122/Z/18/Z
Kidney Research
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Funding agency for:
Issa, F
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
Deposit date:
2020-09-21

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