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What can reinforcement learning models of dopamine and serotonin tell us about the action of antidepressants?

Abstract:

Although evidence suggests that antidepressants are effective at treating depression, the mechanisms behind antidepressant action remain unclear, especially at the cognitive/computational level. In recent years, reinforcement learning (RL) models have increasingly been used to characterise the roles of neurotransmitters and to probe the computations that might be altered in psychiatric disorders like depression. Hence, RL models might present an opportunity for us to better understand the com...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.5334/cpsy.83

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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Publisher:
Ubiquity Press Publisher's website
Journal:
Computational Psychiatry Journal website
Volume:
6
Issue:
1
Pages:
166-188
Publication date:
2022-07-20
Acceptance date:
2022-06-29
DOI:
EISSN:
2379-6227
Language:
English
Keywords:
Pubs id:
1266284
Local pid:
pubs:1266284
Deposit date:
2022-07-01

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