Journal article
Oxygen and mitochondrial inhibitors modulate both monomeric and heteromeric TASK-1 and TASK-3 channels in mouse carotid body type-1 cells.
- Abstract:
-
In rat arterial chemoreceptors, background potassium channels play an important role in maintaining resting membrane potential and promoting depolarization and excitation in response to hypoxia or acidosis. It has been suggested that these channels are a heterodimer of TASK-1 and TASK-3 based on their similarity to heterologously expressed TASK-1/3 fusion proteins. In this study, we sought to confirm the identity of these channels through germline ablation of Task-1 (Kcnk3) and Task-3 (Kcnk9)...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Journal of physiology
- Volume:
- 591
- Issue:
- Pt 23
- Pages:
- 5977-5998
- Publication date:
- 2013-12-01
- DOI:
- EISSN:
-
1469-7793
- ISSN:
-
0022-3751
- Source identifiers:
-
428084
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:428084
- UUID:
-
uuid:7d2d72e8-1ea5-4c94-a922-768a45b8f4e8
- Local pid:
- pubs:428084
- Deposit date:
- 2013-11-16
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- Copyright date:
- 2013
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