Thesis
Peptide targeting by spontaneous isopeptide bond formation
- Abstract:
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Peptide fusion tags are fundamental for the identification, detection, and capture of proteins in biological assays. Commonly used peptide fusion tags rely on temporary non-covalent interactions for binding, which can put constraints on assay sensitivity. Here, peptide fusion tags were developed that could specifically interact with protein binding partners via spontaneous and irreversible isopeptide bond formation. To develop covalently interacting peptide-protein pairs, outer-membrane prote...
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Funding
Bibliographic Details
- Publication date:
- 2011
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- Oxford University, UK
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:7d433538-0fa5-4081-acc5-06c1a77be322
- Local pid:
- ora:6132
- Deposit date:
- 2012-03-15
Terms of use
- Copyright holder:
- Dr. Bijan Zakeri
- Copyright date:
- 2011
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