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The role of the BBSome in Trypanosoma brucei

Abstract:

In humans, 7 genes causing the cilia-related disorder Bardet-Biedl syndrome (BBS) encode proteins that form a complex, named the BBSome. The highly conserved 7 BBSome components facilitate ciliary membrane biogenesis by sorting and transporting specific membrane proteins to the ciliary membrane. The BBSome subunits are also conserved in the protozoan parasite Trypanosoma brucei, the causative agent of African sleeping sickness. T. brucei has been used as a model organism...

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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Oxford college:
Lincoln College
Role:
Author

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Role:
Supervisor
Role:
Supervisor
Publication date:
2012
Type of award:
MSc by Research
Level of award:
Masters
Awarding institution:
Oxford University, UK
Language:
English
Keywords:
Subjects:
UUID:
uuid:7d568a86-de16-415a-807e-139a099ad3f1
Local pid:
ora:7444
Deposit date:
2013-10-10

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