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Journal article

Response of single cells to shock waves and numerically optimized waveforms for cancer therapy

Abstract:

Shock waves are used clinically for breaking kidney stones and treating musculoskeletal indications. The mechanisms by which shock waves interact with tissue are still not well understood. Here, ultra-high-speed imaging was used to visualize the deformation of individual cells embedded in a tissue-mimicking phantom when subject to shock-wave exposure from a clinical source. Three kidney epithelial cell lines were considered to represent normal healthy (human renal epithelial), cancer (CAKI-2)...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.bpj.2017.09.042

Authors


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Institution:
University of Oxford
Division:
MPLS Division
Department:
Engineering Science
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Physiology Anatomy and Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Engineering Science
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Engineering Science
Role:
Author
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Publisher:
Elsevier Publisher's website
Journal:
Biophysical Journal Journal website
Volume:
114
Issue:
6
Pages:
1433-1439
Publication date:
2018-03-27
Acceptance date:
2017-09-28
DOI:
EISSN:
1542-0086
ISSN:
0006-3495
Pmid:
29590600
Source identifiers:
833903
Language:
English
Keywords:
Pubs id:
pubs:833903
UUID:
uuid:7f00f2dd-485b-4ce8-9f30-60607b66179c
Local pid:
pubs:833903
Deposit date:
2018-05-31

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