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Thesis

Hydrogen bonding phase-transfer catalysis: a new approach to asymmetric fluorination

Abstract:

Chapter 1 – Introduction. This chapter aims to highlight the importance of enantioselective fluorination in modern organic chemistry. The peculiar and sometimes contradictory properties of fluorine and fluorinated organic molecules are detailed along with examples of their applications in the life sciences. The origin and the chemistry of fluorinating reagents are also discussed, with a particular emphasis on the fluoride anion’s uses and challenges in organic synthesis. Lastly, a...

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Research group:
Gouverneur Group
Oxford college:
Balliol College
Role:
Author
ORCID:
0000-0002-2739-4156

Contributors

Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Supervisor
ORCID:
0000-0001-8638-5308
More from this funder
Programme:
ISOTOPICS - Isotopic labeling for drug innovation
Funding agency for:
Ibba, F
Grant:
675071
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
Deposit date:
2020-12-16

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