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Journal article

Rhabdovirus matrix protein structures reveal a novel mode of self-association

Abstract:

The matrix (M) proteins of rhabdoviruses are multifunctional proteins essential for virus maturation and budding that also regulate the expression of viral and host proteins. We have solved the structures of M from the vesicular stomatitis virus serotype New Jersey (genus: Vesiculovirus) and from Lagos bat virus (genus: Lyssavirus), revealing that both share a common fold despite sharing no identifiable sequence homology. Strikingly, in both structures a stretch of residues from the otherwise...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.ppat.1000251

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Publisher:
Public Library of Science Publisher's website
Journal:
PLoS Pathogens Journal website
Volume:
4
Issue:
12
Pages:
ARTN e1000251
Publication date:
2008-12-26
Acceptance date:
2008-12-01
DOI:
EISSN:
1553-7374
ISSN:
1553-7366
Source identifiers:
4886
Language:
English
Keywords:
UUID:
uuid:7fd4a537-e778-4d0a-846e-e7194c836862
Local pid:
pubs:4886
Deposit date:
2012-12-19

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