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Thesis

Engineering antibodies to study and improve immunomagnetic isolation of tumour cells

Abstract:

Cell separation based on antibody-targeted magnetic beads has been widely used in a number of applications in immunology, microbiology, oncology and more recently, in the isolation of circulating tumour cells (CTCs) in cancer patients. Although other cell separation techniques such as size based cell filtration and Fluorescence Activated Cell Sorting have also been in popular use, immunomagnetic cell isolation possesses the advantages of high throughput, good specificity and reduced cell s...

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Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Research group:
Dr. Mark Howarth, Prof. Neil Brockdorff
Oxford college:
Keble College
Role:
Author

Contributors

Division:
MSD
Department:
Biochemistry
Role:
Supervisor
Division:
MSD
Department:
Biochemistry
Role:
Supervisor
Publication date:
2013
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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