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Journal article

CD8+ T effector memory cells protect against liver-stage malaria.

Abstract:

Identification of correlates of protection for infectious diseases including malaria is a major challenge and has become one of the main obstacles in developing effective vaccines. We investigated protection against liver-stage malaria conferred by vaccination with adenoviral (Ad) and modified vaccinia Ankara (MVA) vectors expressing pre-erythrocytic malaria Ags. By classifying CD8(+) T cells into effector, effector memory (T(EM)), and central memory subsets using CD62L and CD127 markers, we ...

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Publication status:
Published

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Publisher copy:
10.4049/jimmunol.1100302

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
Journal:
Journal of Immunology
Volume:
187
Issue:
3
Pages:
1347-1357
Publication date:
2011-08-01
DOI:
EISSN:
1550-6606
ISSN:
0022-1767
Language:
English
Keywords:
Pubs id:
pubs:163954
UUID:
uuid:81e88517-696e-408a-af83-dea9905f3304
Local pid:
pubs:163954
Source identifiers:
163954
Deposit date:
2012-12-19

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