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Thesis

Actions of NAADP and other agents in cardiac myocytes

Abstract:

Modulation of cardiac rate and contraction through calcium-dependent and independent means are of central import to the ability of an organism to adapt to its environment.

Nicotinic acid adenine dinucleotide phosphate (NAADP) is a potent calcium-releasing second messenger across a broad range of tissues and organisms. In cardiac myocytes, NAADP is thought to stimulate calcium release from acidic stores which then bolsters filling and release during CICR. Questions remain: as to the ...

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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Research group:
Terrar
Oxford college:
Balliol College
Role:
Author

Contributors

Division:
MSD
Department:
Pharmacology
Role:
Supervisor
Division:
MSD
Department:
Pharmacology
Role:
Supervisor
Publication date:
2014
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:8463cf89-a405-4880-9aad-6fa6ebac542d
Local pid:
ora:10831
Deposit date:
2015-04-08

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