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Conference item

Maternal circulating levels of syncytiotrophoblast vesicles expressing Dipeptidyl Peptidase IV (DPPIV) are increased in Gestational Diabetes Mellitus

Abstract:

Gestational Diabetes Mellitus (GDM) is the most common metabolic disorder of pregnancy. Plasma of women with GDM display lower levels of glucagon-like peptide-1 (GLP-1), which increases insulin secretion and thus regulates glucose homeostasis. GLP-1 concentration normalizes after delivery; suggesting placental involvement in regulating maternal glucose-dependent insulin secretion. The syncytiotrophoblast of the human placenta produces and secretes extracellular vesicles (STBEVs) into the mate...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Women’s & Reproductive Health
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Women’s & Reproductive Health
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Social Sciences Division
Department:
Said Business School
Role:
Author
Publisher:
Elsevier Publisher's website
Host title:
Placenta
Journal:
2018 International Federation of Placenta Associations Meeting (IFPA 2018) Journal website
Volume:
69
Pages:
E7
Publication date:
2018-09-10
DOI:
EISSN:
1532-3102
ISSN:
0143-4004
Pubs id:
pubs:921715
UUID:
uuid:84b99b07-03ae-41f8-a3fc-6545b0b487cc
Local pid:
pubs:921715
Source identifiers:
921715
Deposit date:
2018-10-02

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