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Journal article : Review

Hallmarks and detection techniques of cellular senescence and cellular ageing in immune cells

Abstract:

The ageing of the global population brings about unprecedented challenges. Chronic age-related diseases in an increasing number of people represent an enormous burden for health and social care. The immune system deteriorates during ageing and contributes to many of these age-associated diseases due to its pivotal role in pathogen clearance, tissue homeostasis and maintenance. Moreover, in order to develop treatments for COVID-19, we urgently need to acquire more knowledge about the aged immu...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1111/acel.13316

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Oxford college:
Somerville College
Role:
Author
ORCID:
0000-0002-4077-7995
Kennedy Institute More from this funder
Publisher:
Anatomical Society Publisher's website
Journal:
Aging Cell Journal website
Volume:
20
Issue:
2
Article number:
e13316
Publication date:
2021-02-01
Acceptance date:
2021-01-09
DOI:
EISSN:
1474-9726
ISSN:
1474-9718
Pmid:
33524238
Language:
English
Keywords:
Subtype:
Review
Pubs id:
1161047
Local pid:
pubs:1161047
Deposit date:
2022-01-24

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