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Thesis

The evolutionary dynamics of neutral networks: lessons from RNA

Abstract:

The evolutionary options of a population are strongly influenced by the avail- ability of adaptive mutants. In this thesis, I use the concept of neutral networks to show that neutral drift can actually increase the accessibility of adaptive mu- tants, and therefore facilitate adaptive evolutionary change. Neutral networks are groups of unique genotypes which all code for the same phenotype, and are connected by simple point mutations. I calculate the size and shape of the networks in a small ...

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Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Research group:
Animal Behaviour Research Group
Oxford college:
Magdalen College
Role:
Author

Contributors

Division:
MPLS
Department:
Zoology
Role:
Supervisor
Publication date:
2008
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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