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Thesis

Interrogating the intersection of genetic- and gender-based risk for multiple sclerosis

Abstract:

Multiple sclerosis (MS) has no effective prevention or cure and only limited treat- ment options. Significant progress has been made in finding genetic susceptibility loci, but it is still mostly unclear how genetic variants associated with disease are implicated in MS pathogenesis. Meanwhile, epidemiologically, it has long been clear that women get MS two or three times more frequently than men do. It is also known that there is substantial sexual dimorphism in immune regulation. Th...

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Division:
MPLS
Department:
Statistics
Role:
Author

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Supervisor
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Funding agency for:
Byrne, EH
Type of award:
MSc by Research
Level of award:
Masters
Awarding institution:
University of Oxford
UUID:
uuid:851d0065-4fd2-4276-87b5-738904cf78a5
Deposit date:
2018-01-12

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