Journal article
Genome-wide mapping of susceptibility to coronary artery disease identifies a novel replicated locus on Chromosome 17
- Abstract:
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Coronary artery disease (CAD) is a leading cause of death world-wide, and most cases have a complex, multifactorial aetiology that includes a substantial heritable component. Identification of new genes involved in CAD may inform pathogenesis and provide new therapeutic targets.The PROCARDIS study recruited 2,658 affected sibling pairs (ASPs) with onset of CAD before age 66 y from four European countries to map susceptibility loci for CAD. ASPs were defined as having CAD phenotype if both had...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, tiff, 591.6KB)
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- Publisher copy:
- 10.1371/journal.pgen.0020072
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Funding
+ "Swedish Heart-Lung Foundation", "Swedish Medical Research Council", "Torsten and Ragnar Söderberg Foundation", "Petrus and Augusta Hedlund Foundation", " Karolinska Institute", "Stockholm County Council"
More from this funder
Funding agency for:
Hamsten, A
Grant:
Swedish Medical Research Council (8691
Bibliographic Details
- Journal:
- PLoS Genetics Journal website
- Volume:
- 2
- Issue:
- 5
- Pages:
- e72
- DOI:
- EISSN:
-
1553-7404
- ISSN:
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1553-7390
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:87c2230f-2bc5-410b-a1b4-a4542a38e070
- Local pid:
- ora:967
- Deposit date:
- 2008-03-14
Related Items
Terms of use
- Copyright holder:
- Farrall, M et al
- Copyright date:
- 2006
- Notes:
-
This article was published by PLos as:Farrall M, Green FR, Peden JF, Olsson PG, Clarke R, et al. (2006) Genome-wide mapping of susceptibility to coronary artery disease identifies a novel replicated locus on Chromosome 17. PLoS Genet 2(5): e72. DOI: 10.1371/journal.pgen.0020072
Copyright: ©2006 Farrall et al. This is an open-access article distributed under the
terms of the Creative Commons Attribution License, which permits unrestricted
use, distribution, and reproduction in any medium, provided the original author
and source are credited.
Funding. This project was initiated under a European Union funded
programme and thereafter received funding from AstraZeneca
AB; RC and HW also acknowledge support from the British
Heart Foundation, and RC from the Medical Research Council. AH
obtained support for this project from the Swedish Heart-Lung
Foundation, the Swedish Medical Research Council (8691), the
Torsten and Ragnar Söderberg Foundation, the Petrus and Augusta
Hedlund Foundation, the Karolinska Institute, and the Stockholm
County Council. In Italy the project was endorsed by GISSI—Gruppo
Italiano per lo Studio della Sopravvivenza nell’Infarto—a collaboration
between the National Association of Hospital Cardiologists
(ANMCO) and the Istituto Mario Negri.
- Licence:
- CC Attribution (CC BY)
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