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HLA-DR3 and DQA1*0401: possible risk factors in Alzheimer's disease

Abstract:

It has been suggested that an immune response may contribute to the pathogenesis of Alzheimer's disease (AD), and therefore several studies have examined the possible association of AD with the Major Histocompatibility Complex (HLA). In order to investigate whether there is susceptibility to AD involving the HLA class II antigens, we studied 97 AD patients and 53 controls. Our study included the HLA-class II subgroups DRB1, DQA1 and DQB1. We also investigated whether there is a significant as...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Journal:
ALZHEIMERS REPORTS
Volume:
2
Issue:
2
Pages:
93-97
Publication date:
1999-03-01
ISSN:
1461-6130
Source identifiers:
37023
Language:
English
Keywords:
Pubs id:
pubs:37023
UUID:
uuid:894d28b6-abf9-4f11-9c8b-f9514f985bdd
Local pid:
pubs:37023
Deposit date:
2012-12-19

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