Thesis
The development and application of novel magnetic resonance spectroscopic and imaging techniques to assess cardiac energetics and substrate handling in the human heart
- Abstract:
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Myocardial energy homeostasis requires an interplay between three stages of energy transduction; the choice of substrate oxidised, the rate of mitochondrial oxidative phosphorylation, and finally transfer of adenosine triphosphate (ATP) to sites of disposal via the intermediate phosphocreatine (PCr). Whilst all three elements are fundamental, until recently, non-invasive assessment was limited to 31Phosphorus magnetic resonance spectroscopy (31P-MRS) assessment of the...
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Authors
Contributors
+ Stefan , N
Role:
Contributor
+ Tyler, D
Role:
Supervisor
+ Rider, O
Role:
Supervisor
Funding
+ British Heart Foundation
More from this funder
Grant:
FS/17/18/32449
Funder identifier:
http://dx.doi.org/10.13039/501100000274
Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- Deposit date:
- 2021-06-18
Related Items
Terms of use
- Copyright holder:
- Apps, A
- Copyright date:
- 2021
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