Thesis
Genetics of ankylosing spondylitis
- Abstract:
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Ankylosing spondylitis (AS) is a common inflammatory arthritis of the spine and other affected joints, which is highly heritable, being strongly influenced by the HLA-B27 status, as well as hundreds of mostly unknown genetic variants of smaller effect. The aim of my research was to confirm some of the previously observed genetic associations and to identify new associations, many of which are in biological pathways relevant to AS pathogenesis, most notably the IL-23/TH17 axis (<...>
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Authors
Contributors
+ Wordsworth, B
Division:
MSD
Role:
Supervisor
+ Pointon, J
Division:
MSD
Role:
Supervisor
+ Evans, D
Division:
MSD
Role:
Supervisor
Funding
+ Henni Mester Scholarship (University College), National Ankylosing Spondylitis Society (NASS)
More from this funder
Funding agency for:
Karaderi, T
Bibliographic Details
- Publication date:
- 2012
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- Oxford University, UK
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:8c0e848a-e712-4603-b923-a96a2f1644ac
- Local pid:
- ora:6934
- Deposit date:
- 2013-07-02
Terms of use
- Copyright holder:
- Karaderi, T
- Copyright date:
- 2013
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